The Institut national d’excellence en santé et en services sociaux was created on January 19, 2011. It succeeded the Conseil du médicament and the Agence d’évaluation des technologies et des modes d’intervention en santé (AETMIS). INESSS’s mission is to promote clinical excellence and the efficient use of resources in the health and social services sector. At the heart of the mission, INESSS assesses, in particular, the clinical advantages and the costs of the technologies, medications and interventions used in health care and personal social services. It issues recommendations concerning their adoption, use and coverage by the public plan, and develops guides to clinical practice in order to ensure their optimal use.